29Sep, 2018

Testosterone metabolism

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The testicle has two basic functions: endocrine (production of hormones) and exocrine (production of sperm). 85-90% of the interior of the testicular volume is made up of seminiferous tubules and their germinal epithelium, the place where sperm are produced (from 10 to 20 million gametes per day), and only 10-15% is occupied by the interstitium, where testosterone is produced. The adult male testicle produces approximately 5 to 7 mg of testosterone per day. Testosterone secretion is adjusted to a circadian rhythm, with late afternoon minima and late evening and early […]
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29Sep, 2018

The Gender And Mental Patterns

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We will start from the scientifically proven premise that there are differences conditioned by the anatomy of the brain and by the exposure to different hormones that determine that in some way the cognitive (perceptive and information processing), emotional and perhaps pulsional models are different between female and male sexes. It is known that prenatal exposure of the fetal brain to androgens (male hormone) at a critical gestational age can irreversibly masculinize the individual’s postnatal behavior. The highest concentration of receptors for this hormone is found in the hypothalamus, the […]
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29Sep, 2018

How the lack of sexual desire affects men

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Although there is no homogeneous pattern in men with regard to sexual performance, there is no doubt that for the perception and self-confidence, the loss of sexual desire is very difficult for them to bear, which puts them in a situation of vulnerability, since we take it for granted that the sexual impulse must be greater in the male. This is also part of the social conception of sexual roles, hence many jokes are made about the topic “men always think the same thing” or that they have to be […]
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29Sep, 2018

Secondary Hypogonadism or Hypogonadotrope in Men

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-Definition: Hypogonadism is a condition in which the testicles in men and the ovaries in women produce little or no sex hormone, with consequent sexual dysfunction and/or infertility. Hypogonadotropic hypogonadism (HH) is a form of hypogonadism that is due to a problem with the pituitary gland or hypothalamus, it is also called secondary. HH is caused by a lack of hormones that normally stimulate the ovaries or testicles: These hormones include gonadotropin-releasing hormone(GnRN), follicle-stimulating hormone (FSH), and luteotropic hormone (LH). -Consequences: The hypothalamus in the brain secretes (GnRH). This hormone […]
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29Sep, 2018

Most frequent causes of lack of libido in men

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Diagnosis: In this section we must differentiate hypogonadism from hypoactive sexual desire and loss of libido, although they often overlap and confuse because they can have a common origin. The disorder of hypoactive sexual desire in the DSM-5 (Diagnostic Manual of Mental Illnesses) currently defines it as follows: it consists of the repeated and persistent absence of sexual fantasies or interest in carrying out some type of sexual activity, without alluding to the partner and on the condition that there is no physical or organic cause to explain it. The […]
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15Sep, 2018

Hypogonadism: When Testosterone Falls

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Two out of five men suffer alterations related to this hormone, the most common being hypogonadism, which occurs when there is a low. Testosterone is usually reduced as wth the age. Its lower production usually translates into problems at the sexual, muscular and even mental level. Sexual health Hypogonadism can lead to sexual failures, such as decreased libido or interest in sex, loss of potency in the sexual organ, reduction of semen volume or lower frequency of erections. Muscular system Muscle development is directly related to testosterone levels, so a […]
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15Sep, 2018

Obesity and psychological traits

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In endocrine diseases, the psychological state must be considered, as this is fundamental for adherence to treatment. Particularly in obesity there may not be a genuine mental disorder, but psychological factors have a fundamental importance in controlling the feeling of satiety, in any case in the obese there may be a primary pathological alteration that originates the problem, likewise could be the result of an abnormal behavior as a reaction to an unresolved problem and it is also necessary to take into account both the alterations that occur as a […]
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15Sep, 2018

ADAM syndrome and ADAM test

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Definition: In the next ten years the prevalence of diseases such as erectile dysfunction (ED), benign prostatic hyperplasia (BPH), prostate cancer and Testosterone deficiency will increase, taking into account the foreseeable longevity of the population. We must bear in mind that more than 70% are unaware of this reality. The ADAM Syndrome, “Androgen Deficiency Aging Male”, is the clinical manifestation of Androgen Deficiency of the Male Age, andropenia or andropause. Consequences of androgenic deficiency Less intellectual agility, concentration, memory and spatial orientation, is what is called cognitive changes. Tendency to […]
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15Sep, 2018

Insensitivity to mild androgens

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Definition: Mild androgen insensitivity syndrome is a condition that results in a mild impairment of the cell’s ability to respond to androgens. The degree of impairment is sufficient to jeopardize spermatogenesis and/or the development of secondary sexual characteristics at puberty in men, but does not affect genital differentiation or development, it is also known as: Mild androgen insensitivity syndrome (MAIS). The clinical phenotype associated with MAIS is a normal male type with mild spermatogenesis defects and/or secondary terminal hair reduction. It should not be confused with the complete androgen insensitivity […]
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1Sep, 2018

Xenoandrogens as hormone disruptors

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Introduction: Xenoandrogenics were first described in 2008 by Professor I. Morishita of Kyoto University and his team, whose scientific work described how all alpha-tocopherol modified racemic acetate stimulates RA receptor in some mammalian species. What about Xenoandrogens? Xenoandrogen: Xenoandrogen is a group of artificially created compounds with properties similar to the human steroid hormone testosterone and its derivatives. Currently known xenoandrĂ³genos include modified tocopherols and tocotrienols, modified nicotinamides and tributyltin, triphenyltin and toxic methylestestosterone. Use to increase performance: They have not been commercially available until the second half of 2011, […]
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