22Dec, 2018

Free testosterone is the most important factor

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The androgen testosterone (17βhidroxiandrostenona) has a molecular weight of 288 Daltons. In the male sex, testosterone is synthesized almost exclusively by the Leydig cells of the testicle. Its secretion is regulated by the luteinizing hormone (LH) and responds to negative feedback from the hypophysis and hypothalamus. SHBG is strongly attached to three sex hormones found in both men and women: estrogen, dihydrotestosterone or DHT, and testosterone. SHBG carries these three hormones through the blood. Although SHBG fixes three hormones, the hormone that is fundamental in this analysis is testosterone. The […]
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22Dec, 2018

Fertile Spermiogram Evaluation

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-Definition According to the reference values established by the World Health Organization (WHO), a fertile male must have at least 15 million spermatozoa per milliliter of semen. The progressive motility of the sperm should be more than 32% and the morphology is normal (without anomalies) should be more than 4%. The morphology of the spermatozoa is a characteristic that is studied in the spermiogram (it is the same as the seminogram) to see if there are abnormal spermatozoa in the semen, in what quantity they are found and what alterations […]
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8Dec, 2018

Importance of Kisspeptine

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-Definition The kisspeptine is a hormone and neurotransmitter in its functioning in the brain, as a hormone is linked to the regulation of sexuality and affection, among other things. And it is a hormone that could have applications in the treatment against cancer. Kisspeptine is linked to the inhibition of metastasis and the genesis of emotions related to affective bonding and sexual behavior. It was discovered in 1996. In fact, it was initially called metastine because its discovery was associated with the suppression of metastasis. It would not be until […]
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8Dec, 2018

Aromatase Is Important

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-Definition: Androstenedione and testosterone are converted into estrone and estradiol, respectively, by the activity of aromatase, an enzyme located inside several cell types of the gonads. The catalytic active complex is composed of a cytochromeP450 aromatase. The gene encoding this protein is CyP19 and depending on the tissue and species, the aromatase possesses between 490 and 525 amino acids. Steroid hormones, once synthesized, are secreted to the general circulation or lymphatic system to be transported and then specifically captured by their respective target organs. When released into circulation, gonadal steroids […]
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