Leptin, insulin, estrogens, androgens, cortisol and growth hormone hormones influence our appetite, metabolism and fat corporal.Las people who are obese have levels of hormones that promote the accumulation of body fat.
Hormones are chemical messengers that regulate metabolic processes in the body. They are one factor in causing obesity. The hormones leptin and insulin, sex hormones, cortisol and growth hormone influence appetite, metabolism (the rate at which our body burns calories for energy), and the distribution of body fat. People who are obese have lower levels of these hormones that promote abnormal metabolism and accumulation of body fat.
A set of glands known as the endocrine system secretes hormones into our bloodstream. The endocrine system works with the nervous system (in the sense that transmit messages remotely or signals, in the case of hormones will rush circualatorio), and the immune system to help the body cope with the different situations and tensions. Excesses or deficiencies of hormones can lead to obesity and, on the other hand, obesity can lead to changes in hormones.
Cortisol and obesity:
When fat accumulates in the presence of cortisol it is visceral fat (surrounding the viscera) to facilitate the movement as in such areas are larger blood vessels and it would burst hand faster. This type of obesity is related to the development of cardiovascular disease, type II diabetes and cerebrovascular diseases.
Cortisol response depends on each individual, not all respond to the same degree in the same situation. Cortisol also indirectly influences appetite by regulating other chemicals that are released during stress as CRH (corticotropin releasing hormone), leptin and neuropeptide Y (NPY)
What is recommended is that in addition to eating well and getting enough rest and get some exercise outdoors, if possible, should include some method for managing stress in those who have elevated cortisol.
This cortisol if high pathologically, is produced by an adenoma either adrenal or pituitary and is known as Disease or Syndrome Cushing.También can be caused by multiple treatments using cortisone, which is a form of exogenous cortsol, that is supplied from outside, either as a medicine to treat various diseases in both humans and their pets, as we share many of their genes and often diseases and treatments are similar.
Obesity and leptin:
The hormone leptin is produced by fat cells and is secreted into our bloodstream. Leptin reduces a person’s appetite by acting on specific brain centers to reduce your desire to eat. Also appears to control how the body handles fat book corporal.Debido that leptin is produced by fat, leptin levels tend to be higher in people who are obese than in normal-weight people. However, despite having higher levels of this hormone appetite-reducing, people who are obese are not as sensitive to the effects of leptin and as a result, tend not to feel full during and after a meal.
Obesity and insulin:
Insulin, a hormone produced by the pancreas, is important for the regulation of carbohydrate and fat metabolism. Insulin stimulates the uptake of glucose (sugar) in the blood in tissues such as muscle, liver and fat. This is important to ensure that energy is available for daily operation and to maintain normal glucose levels of circulating process.
A person who is obese, insulin signals are sometimes lost and tissues are no longer able to control glucose levels. This can lead to the development of Type II diabetes and metabolic syndrome.
Obesity and neuropeptide Y (NPY)
This hormone is a potent stimulator of appetite and when stress occurs NPY levels increase, causing among other things that heart rate and blood pressure increase, there is a connection between stress, high-calorie diets and gain weight. A stress-free mice were fed a normal diet and a high calorie diet. The stressed and unstressed animals ate the same high calorie food, but the stressed animals utilized and stored fat differently, and gained twice as much weight.
The results suggest that could reverse or prevent obesity caused by stress and diet, which makes people who suffer are more susceptible to heart disease and diabetes. In animal models, in which the NPY receptor is blocked or has been eliminated them abdominal adipocytes gene it has been observed that stressed mice with high-calorie diets do not suffer from obesity. Even other adverse effects related to stress and diet, which include glucose intolerance and fatty liver are reduced.
Obesity and sex hormones:
The distribution of body fat plays an important role in the development of obesity-related conditions such as heart disease, stroke and some forms of arthritis. The fat around our abdomen is a major risk factor for the disease than fat stored in the belly, hips and thighs. It seems that estrogens and androgens help decide the distribution of body fat. Estrogens are sex hormones produced by the ovaries in pre-menopausal women. They are responsible for triggering ovulation in each menstrual cycle, are also found in man as the fat is an enzyme (a protein that acts as a catalyst and facilitates a chemical reaction) which converts testosterone into estradiol,
In younger men, androgens are produced at high levels in the testes. As men age, these levels gradually decline.
Changes with age in the levels of sex hormones in men and women are associated with changes in the distribution of body fat. While women of childbearing age tend to store fat in their lower body ( “pear-shaped”), older men and postmenopausal women tend to increase fat storage around your abdomen ( “apple shape”) .
Obesity and growth hormone:
The pituitary gland in the brain produces growth hormone, which influences the height of a person and helps build our bones and muscles. Growth hormone also affects metabolism (the rate at which calories are burned energy). Researchers have found that levels of growth hormone in people who are obese are lower than people of normal weight.
inflammatory factors and obesity:
Obesity is also associated with chronic low-grade inflammation in fat tissue. storing excess fat leads to stress reactions in fat cells, which in turn can lead to the release of proinflammatory factors own fat cells and immune cells in adipose tissue (fat).
Obesity is associated with an increased risk of a number of diseases, including cardiovascular disease, stroke and various cancers, and decreased longevity (shorter life), lower quality of life and reduced sexual performance . Appetite regulation is an extraordinarily complex process that only now beginning to be elucidated Recent research shows can act on the multiple factors that affect it and that such actions must be interconnected with each other as they are controlling caloric intake, control glycemic index, the composition of food habits and lifestyle and practice exercises.
It should be borne in mind that Viagra-type drugs are not always effective if testosterone does not have a adeacuados levels.
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