Viagra Type Medications

By: | Tags: | Comments: 0 | May 26th, 2018

-The inhibitors of DPE5

Erectile dysfunction (ED) is the inability to achieve or maintain an adequate erection for satisfactory sexual performance. It should be noted that ED may be a consequence of certain risk factors such as high blood pressure and diabetes, as we have already commented in other articles of this blog. Likewise, those suffering from diabetes or obesity are characterized by higher rates of ED in relation to the general population, with a prevalence that increases according to age and duration of the disease.
Phosphodiesterase type 5 (PDE5) inhibitors, such as sildenafil, vardenafil, and tadalafil, are the most frequent treatment for ED, since they are effective, safe, and well-tolerated drugs, and were launched in 1998 (initially it was only viagra), it has represented the second sexual revolution after the appearance of the contraceptive pill in the 50s of the last century.


However, it is estimated that only 10% of affected men perform a medical consultation in search of treatment, while approximately 30% of patients, leave the proposed treatment.


Although the best known of those mentioned is sildenafil, being the first to appear on the market, with a commercial name of viagra, there are others such as vardanafilo, with a commercial brand of levitra and avanafilo with a commercial name of spedra.
Tadalafil, commercially called cialis, there are 5, 10 and 20 mg per tablet, has shown a longer duration of the response period, allowing the patient to choose, during the 36 hours, the ideal moments to maintain a successful sexual relationship and satisfactory, among the advantages of this drug are the following:


1- Its effectiveness lasts for more than 36 hours.
2- It increases its action before the erotic stimuli.
3- Its effectiveness is not modified by the intake of any type of food.
4- He begins to act at 30 minutes, but his greatest action is approximately after two hours of ingestion.
5- It is suitable for diabetic or hypertensive patients.
6-One of the drawbacks is that by taking the other inhibitors of PDE5, an expectation is created and the patient practically has to wait to see the response and that generates anxiety for him and his partner, which does not happen with cialis having a long half-life, everything can happen with normality and without expectation, this singularity, causes some to call it the weekend pill, its launch goes back to 2003.


In clinical trials, men with erectile dysfunction had greater self-confidence, with higher sexual spontaneity and fewer intrusive concerns related to sexual encounters when treated with tadalafil compared to sildenafil.


This explains why more men mostly prefer tadalafil for the treatment of erectile dysfunction, when a doctor tells you these advantages.
Tadalafil, like the other drugs of this family, is an inhibitor of the enzyme phosphodiesterase type 5 that, by ceasing this enzyme degrading cyclic GMP (which produces the release of nitric oxide and the consequent vasodilation in the corpora cavernosa of the penis) It allows to get erections with greater firmness and duration.


Avoiding the loss of the rigidity that so anguishes patients, which leads them to try premature ejaculation for fear of losing the erection or abandon the attempt to reach the climax with all the feeling of frustration that this entails, and even improves the spontaneous nocturnal erections.

-Other therapeutic uses:

In patients with pulmonary arterial hypertension, therapy with 40 mg of tadalafil has been shown to be well tolerated and improves exercise capacity and quality of life parameters, in addition to reducing physical deterioration caused by the disease.
Pulmonary arterial hypertension (PAH) is a disease of unknown and progressive origin that is characterized by a chronic elevation of pulmonary arterial pressure, which often leads to right heart failure.


It is also indicated in the treatment of benign prostatic hyperplasia, either alone or in combination with other medications.


It is frequent, that a man, whatever his age, after having a sexual encounter, which has not been satisfactory, that situation affects his self-esteem, therefore it is important to make sure, that the mentioned negative experiences are not repeated, since that can lead to a psychological loop, this effect that I would call talisman, is very important when you resort to this type of medicine and it is absurd, to consider it as something unnatural or artificial.


Obviously, as we have already explained in this blog, we have to make sure that there is no hormonal deficit, since the success of the medication will depend on a basic normality of testosterone and an indemnity of the vascular endothelium to produce nitric oxide.

 

-10 tips to get a good erection:

1. Think about obtaining and giving pleasure to the couple, as far as possible, with a reciprocal and spontaneous synchronicity and complicity.


2. Sexuality is a game and a way to have fun between two people, who at least have a mutual attraction.


3. Forget the obligation to look good, always and at all costs, anticipating the facts.


4. Do not keep all the responsibility of the burden of the sexual relationship, but think that it is a shared enjoyment since the two parties involved would have to put 50 percent and the actor is not one.


5. The first is to take into account that penetration is not the priority and must be preceded by other practices such as kissing, licking, fondling or other games, or mutual masturbation, given that if you reach that extreme, you do not have to be nothing shameful.


6. Nothing happens to lose the erection due to causes such as being more focused on the satisfaction of the couple. It is possible to recover it after a while, but for this it is important to not get carried away by stage fright or anticipatory.


7. Do not abuse alcohol or other substances to disinhibit and lose false fears of not having a good performance, it is not an end-of-career test.


8. Enjoy the moment that produces a shared pleasure, in every relationship there must be appreciation, affection and respect,if possible love is also desirable although, nothing is eternal.


9. We should only focus on the here and now, without getting distracted by what happened before, either yesterday, in the remote past or in the future, whether near or far.


10. Use fantasy as something that is not reprehensible, rather on the contrary, necessary to avoid falling into the routine and be aware of what we do, since we are not sexed vegetables.

 

-Conclusions:


Obviously these recommendations are drigidas people mentally within the average considered healthy and discard everything that deviates from normal, not to be strongly, object of our blog.


Such is the safety and safety of this family of medicines that soon, in the United Kingdom, will be marketed a “viagra”, accessible without a prescription, consequently, it is illogical, to deduce that the benefits may be harmful, unless have heart disease treated with nitrates or other diseases or treatments that contraindicate its use or that is used indiscriminately and repeatedly to gain safety, which can lead to psychological dependence.


We must also bear in mind that there are many men whose erectile dysfunction is a sentinel symptom of a underlying or undetected pathology, whether it is diabetes, hypertension, high cholesterol or some cardiovascular pathology and they do not know it.

Therefore, we are of the opinion that you should go to the specialist before taking this medication for the first time and with annual follow-up checks, if you are older than 35 years.

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