9Feb, 2020

Apolipoproteins and Cholesterol

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-Summary: Dehydroepiandrosterone (DHEA) is an endogenous prohormone secreted by the adrenal glands and only 10% by the genitals, both ovaries and testicles. It is a precursor of androgens and estrogens. DHEA is also a neurotransmitter steroid, also known as a neuromediator, it is a chemical whose main function is the transmission of information from one neuron to another through the space called synaptic that separates two consecutive neurons. -Development: As a neuroactive steroid, dehydroepiandrosterone (DHEA), activates the receptor, sigma1, which has a neuroprotective action, eliminating free radicals, as well as […]
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9Feb, 2020

Apolipoproteínas y Colesterol

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-Resumen: La medición de niveles plasmáticos de apolipoproteínas indican con mayor fiabilidad el riesgo cardiovascular, inclusive puede ser un indicador más fiable de enfermedad cardiovascular que los niveles de colesterol LDL. Hasta hace poco, se medían las concentraciones del colesterol total HDL y LDL como primer índice del riesgo de enfermedad cardiovascular. -Desarrollo: Actualmente está siendo superior la proporción apolipoproteína B/ apolipoproteína A-1, ya que,la apolipoproteína A-I (Apo A-I) es una proteína que juega un papel específico en el metabolismo de los lípidos, siendo el principal componente proteico de las […]
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9Feb, 2020

DHEA and its Importance

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-Summary: Dehydroepiandrosterone (DHEA) is an endogenous prohormone secreted by the adrenal glands and only 10% by the genitals, both ovaries and testicles. It is a precursor of androgens and estrogens. DHEA is also a neurotransmitter steroid, also known as a neuromediator, it is a chemical whose main function is the transmission of information from one neuron to another through the space called synaptic that separates two consecutive neurons. -Development: As a neuroactive steroid, dehydroepiandrosterone (DHEA), activates the receptor, sigma1, which has a neuroprotective action, eliminating free radicals, as well as […]
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9Feb, 2020

La DHEA y su Importancia

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-Resumen: La dehidroepiandrosterona (DHEA) es una prohormona endógena secretada por las glándulas suprarenales y solo un 10% por los genitales, tanto ovarios como testículos. Es un precursor de los andrógenos y estrógenos. DHEA es también es un esteroide neurotransmisor, también conocido como neuromediador, es decir, es una sustancia química cuya principal función es la transmisión de información de una neurona a otra atravesando aquel espacio denominado como sináptico que separa dos neuronas consecutivas. -Desarrollo: Como esteroide neuroactivo, la dehidroepiandrosterona (DHEA), activa el receptor, sigma1, que tiene acción neuroprotectora, eliminando radicales […]
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27Oct, 2019

Isolated LH Deficiency

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-Summary: LH is not necessary for the differentiation of the genitals in the male sense. In fact, in our species, HCG (human chorionic gonadotropin) produced by the placenta, very homologous to LH, will allow the masculinization of the genital organs before birth by acting on the same LHR receptor. However, after birth, LH is essential for testicular maturation, especially for the proliferation and maturation of Leydig cells, which will acquire the ability to secrete testosterone, allowing pubertal virilization and activation of spermatogenesis. -Development: About 15% of couples are infertile and […]
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27Oct, 2019

Importance of OH-progesterone

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-Summary: 17-hydroxy-progesterone (17α-OH-P) is a steroid produced in the adrenal glands and gonads (testicles or ovaries). It is a natural progestogen, and is increased during the third trimester of pregnancy mainly due to fetal adrenal production. As a hormone, 17OHP also interacts with progesterone receptors. -Development: Normal levels in children are 3-90 ng/dl, in men: 139 ng/dL (< 4.17 nmol/L) and in women: it depends on the stage of the ovarian cycle: Follicular phase: 0.2 – 2.6 ng/ml Luteal phase: 0.35 – 4.0 ng/dL Postmenopause: 0.1-1.2 ng/ml Congenital adrenal hyperplasia […]
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27Oct, 2019

Estradiol and Male Reproductive Function

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-Summary: Traditionally, testosterone and estrogen have been considered male and female sex hormones, respectively. However, estradiol, the predominant form of estrogen, also plays a role in male sexual function. Estradiol in men is essential for libido modulation, erectile function, and spermatogenesis. -Development: Estrogen receptors, as well as aromatase, the enzyme that converts testosterone into estrogen, are abundant in the brain, penis and testicles, organs important for sexual function. In the brain, estradiol synthesis increases in areas related to sexual arousal. In addition, in the penis, estrogen receptors are found throughout […]
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13Jul, 2019

Haemospermia or Hematospermia

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Haemospermia or Hematospermia -Summary: Hematospermia or haemospermia is a very disturbing symptom among men, but can be managed in many cases without further complications. Because it is not a habitual demand in consultation, it requires epidemiological knowledge and an adequate clinical judgment in order to be able to approach each case correctly and reassure our patients. -Introduction: Hematospermia or haemospermia is defined as the presence of blood in the semen or sperm. The most frequent cases are in men between 30 and 40 years old. It is recurrent: when it […]
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13Jul, 2019

Delayed Puberty

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-Summary: Delayed Puberty is the absence of secondary sexual characteristics, of 2 standard deviations from the average age of onset of normal puberty in the population and sex to which the individual belongs. In practical and temporal terms, for men it is at the age of 14, when the testicular volume is less than 4 ml and for women it is at the age of 13, when there is still no presence of telarquia (start of the mammary button). -Introduction: Puberty is the period in which sexual maturation is completed […]
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18May, 2019

Abdominal Fat and Sexual Dysfunction

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-Introduction Overweight and obesity are associated with metabolic syndrome and insulin resistance and both have an effect on sexual function. However, the presence of abdominal obesity correlates more strongly with cardiovascular risk factors than a high body mass index (BMI). Therefore, waist circumference measurement is recommended in order to identify the corresponding body weight component of the metabolic syndrome and more than 50% of obese people have a low free testosterone. Some male patients may develop multiple metabolic risk factors when the waist circumference is only increased to a negligible […]
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